Middleton, Emily Ruth

Grant Type: 
Dissertation Fieldwork Grant
Insitutional Affiliation: 
New York U.
Status: 
Completed Grant
Approve Date: 
April 16, 2013
Project Title: 
Middleton, Emily Ruth, New York U., New York, NY - To aid research on 'Ecogeographical Influences on Trunk Modularity in Recent Humans: Colonization and Morphological Integration,' supervised by Dr. Susan C. Anton

Preliminary abstract: One of the core issues in paleoanthropology concerns the evolution of human body form -- changes in size, shape, and structure of the skeleton -- and the selective pressures influencing that evolution. The ribcage, spine, and pelvis have undergone numerous shape changes throughout our evolutionary history as we shifted from tree-dwelling apes to upright creatures who walk around on two legs, give birth to large-brained babies, and possess the unique ability to live in all types of global environments. Unlike studies that look at different regions of the skeleton in isolation, my research investigates the relationships between the bony elements of the trunk to test how changes in the shape of the hipbone, for example, affect the spine and vice versa. My research also examines the relationship between shape and environment to explore if humans have a novel, complex ability to adapt to climate in a way unlike other mammals. Looking at how the ribcage, spine, and pelvis are interrelated and how each of these regions varies with climate provides clues about how our body responds to selection. Elucidating these relationships is critical for understanding how body form in human ancestors responded to the challenges posed by difficult obstetrics and novel environments.

Grant Year: 
2013
Award Amount: 
$15,215

Snodgrass, James Josh

Grant Type: 
Dissertation Fieldwork Grant
Insitutional Affiliation: 
Northwestern U.
Status: 
Completed Grant
Approve Date: 
May 7, 2002
Project Title: 
Snodgrass, James J., Northwestern U., Evanston, IL - To aid research on 'Energetics, Health, and Lifestyles Change among the Yakut of Siberia,' supervised by Dr. William R. Leonard

JAMES J. SNODGRASS, Northwestern University, Evanston, Illinois, received funding in May 2002 to aid research on 'Energetics, Health, and Lifestyles Change among the Yakut of Siberia,' supervised by Dr. William R. Leonard. This study examined the health consequences of economic modernization in the Yakut (Sakha), a high-latitude indigenous population of horse and cow pastoralists from the Sakha Republic of Russia. The two main research objectives were: 1) to investigate metabolic adaptation; and 2) to explore health and energy balance within the context of economic modernization. All research was conducted in the rural Siberian village of Berdygestiakh, Russia. Data were collected on: basal metabolic rate (BMR), total energy expenditure (TEE), blood pressure, body composition, diet, thyroid hormones, Epstein-Barr virus antibodies, and lifestyle and socioeconomic status. The results of this study indicate that, regardless of which reference standard is used, Yakut men and women have elevated BMRs. This study did not document any significant relationships between lifestyle measures and BMR, which suggests that genetic factors play an important role in metabolic elevation. This research provides baseline information on health and energy balance in the Yakut and investigates how specific lifestyle (e.g., physical activity and diet) and socioeconomic (e.g., income and education) factors contribute to the development of obesity and hypertension. Relatively low levels of physical activity, documented using the doubly labeled water technique, play an important role in the development of obesity in the Yakut, especially among women. Obesity and hypertension are emerging health issues among the Yakut. Affluence is associated with obesity among men, but not women; this parallels findings from nationally representative studies in Russia that document that health changes are more closely tied to socioeconomic status in men than women.

Publication Credits:

Snodgrass, J. Josh, William R. Leonard, M.V. Sorensen, L.A. Tarskaia, and M.J. Mosher. 2008. The Influence of Basal Metabolic Rate on Blood Pressure among Indigenous Siberians. American Journal of Physical Anthropology 137(2):145-155

Snodgrass, J.J., M.V. Sorensen, L.A. Tarskaia, and W.R. Leonard. 2007. Adaptive Dimensions of Health Research among Indigenous Siberians. American Journal of Human Biology 19:165-180.

Snodgrass, J.J., W.R. Leonard, L.A. Tarskaia, T.W. McDade, et al. 2007. Anthropometric Correlates of C-Reactive Protein among Indigenous Siberians. Journal of Physiological Anthropology 26:241-246.

Snodgrass, J. Josh, et al. 2006. The Emergence of Obesity among Indigenous Siberians. Journal of Physiological Anthropology 25(1):75-84.

Snodgrass, J. Josh, et al. 2006. Total Energy Expenditure in the Yakut (Sakha) of Siberia as Measured by the Doubly Labeled Water Method. American Journal of Clinical Nutrition 84:798-806.

Snodgrass, J. Josh, W.R. Leonard, L. Tarskaia, V.P. Alekseev, and V.G. Krivoshapkin. 2005. Basal Metabolic Rate in the Yakut (Sakha) of Siberia. American Journal of Human Biology 17:155-172.

Grant Year: 
2002
Award Amount: 
$20,000

Eaves-Johnson, K. Lindsay

Grant Type: 
Dissertation Fieldwork Grant
Insitutional Affiliation: 
Iowa, U. of
Status: 
Lapsed Grant
Approve Date: 
May 7, 2008
Project Title: 
Eaves-Johnson, K. Lindsay, U. of Iowa, Iowa City, IA - To aid research on 'A Spirometric and Geo-Morphometric Baseline for the Study of Thoracic Patterning in Fossil Homo,' supervised by Dr. Robert Gary Franciscus

Preliminary abstract: Due to a general, though undocumented, sense that little diagnostic information can be gleaned from them, ribs and overall thoracic morphology have been comparatively understudied relative to other anatomical regions in human paleontology. This study tests the influence of skeletal thoracic shape on respiratory variables (e.g., total lung capacity, functional residual capacity, etc.) using computed tomography (CT), to expand our understanding of modern and Neandertal thoracic patterning. The mixed-sex CT sample consists of 50 respiratorily normal subjects and 10 subjects with chronic obstructive pulmonary disorder (COPD), all between the ages of 20 and 60 (IRB: 199708651). This homogenous, living CT sample is compared with a regionally heterogeneous, mixed-sex skeletal sample from the extremes of human variation (n=134), as well as the Neandertal specimens Kebara 2, Tabun C1, Shanidar 3, and La Chapelle. Preliminary results suggest that, while gross spirometric measures, such as total lung capacity agree well with the predicted model, further study is needed to delineate the skeletal parameters most amenable to comparison for such variables as functional residual capacity. Additionally, comparisons of the Levantine Neandertals with the modern sample fail to demonstrate any significant temporal excursion from the range of modern variability with respect to these parameters.

Grant Year: 
2008
Award Amount: 
$13,473

Howells, Michaela Emily

Grant Type: 
Dissertation Fieldwork Grant
Insitutional Affiliation: 
Colorado, Boulder, U. of
Status: 
Completed Grant
Approve Date: 
April 18, 2011
Project Title: 
Howells, Michaela Emily, U. of Colorado, Boulder, CO - To aid research on 'The Impact of Psychosocial Stress on Gestation Length and Pregnancy Outcomes in American Samoa,' supervised by Dr. Darna Dufour

MICHAELA E. HOWELLS, then a student at University of Colorado, Boulder, Colorado, was awarded funding in April 2011 to aid research on 'The Impact of Psychosocial Stress on Gestation Length and Pregnancy Outcomes in American Samoa,' supervised by Dr. Darna Dufour. The objective of this research is to determine the relationship between chronic maternal psychosocial stress on spontaneous abortion, gestation length, and neonate body size. In order to achieve this goal, the grantee conducted a biocultural, longitudinal, prospective study of pregnancy outcomes in 184 women experiencing significant shifts in cultural identity in American Samoa. Two interrelated indicators of psychosocial stress -- Epstein-Barr virus (EBV) antibody concentration and status incongruence -- were paired with monthly maternal interviews to assess the effects of stress on pregnancy outcomes. EBV antibody concentrations represent a broad, non-specific response to psychosocial stressors. Status incongruence is related to a woman's status within the community and arises when an individual is unable to resolve traditional and nontraditional markers of status. This study follows from their first prenatal care appointment through to their pregnancies natural conclusion and will help clarify the effects of psychosocial stress on pregnancy outcomes. Pregnancy outcomes will be assessed in terms of neonate size for gestation. Possible outcomes include spontaneous abortions, preterm births (? 36 weeks) and full-term births. This study aims to add to our knowledge of the factors associated with pregnancy loss, premature delivery, and infants born small-for-gestational-age in a non-western population of women.

Grant Year: 
2011
Award Amount: 
$24,800

Nelson, Robin Gair

Grant Type: 
Post-Ph.D. Research Grant
Insitutional Affiliation: 
Skidmore College
Status: 
Completed Grant
Approve Date: 
April 8, 2011
Project Title: 
Nelson, Dr. Robin Gair, Skidmore College, Saratoga Springs, NY - To aid research on 'Residential Context, Non-Kin Care and Child Health Outcomes in Jamaica'

DR. ROBIN G. NELSON, Skidmore College, Saratoga Springs, New York, was awarded a grant in April 2011 to aid research on 'Residential Context, Non-Kin Care and Child Health Outcomes in Jamaica.' This study explores the relationship between residential context, parental investment, and child health outcomes in Jamaica. It centers on an examination of the growth and development of children living in state-sponsored homes, and children who are living with biological family members. Ethnographic, anthropometric, and biometric data were collected from 125 children living in state-sponsored children's homes, and 119 children living with their biological family members in Manchester Parish. Follow-up data were collected from 70 of 125 children who were still living in childcare facilities. Preliminary analyses reveal statistically significant correlations between residence in a state-sponsored care setting and anthropometric health indicators. There are also statistically significant gendered differences in the health outcomes between girls and boys living in these state-sponsored homes. These findings parallel ethnographic data detailing highly variable and gendered childcare practices in these homes. Future analyses will compare anthropometric and biometric data of children living with biological kin, and that of their peers living in the children's homes. These findings aid in our understanding of the ways that variability in kin investment and care setting come to correlate to particular health outcomes. This study navigates the intersection of evolutionary theory and biocultural studies of child care practices and health outcomes.

Grant Year: 
2011
Award Amount: 
$23,769

Thayer, Zaneta Marie

Grant Type: 
Dissertation Fieldwork Grant
Insitutional Affiliation: 
Northwestern U.
Status: 
Completed Grant
Approve Date: 
April 8, 2011
Project Title: 
Thayer, Zaneta Marie, Northwestern U., Evanston, IL - To aid research on 'Intergenerational Programming of Stress Reactivity: Role of Epigenetic Mechanisms,' supervised by Dr. Christopher Kuzawa

ZANETA THAYER, then a student at Northwestern University, Evanston, Illinois, received funding in April 2011 to aid research on 'Intergenerational Programming of Stress Reactivity: The Role of Epigenetic Mechanisms,' supervised by Dr. Christopher Kuzawa. Anthropologists have a long history of studying biological responses to environmental stress from diverse perspectives. Within our field the effects of maternal psychosocial stress on biology and health in the next generation is becoming a topic of increased interest. This research project evaluated the intergenerational effects of maternal stress experience among an ethnically and socioeconomically diverse sample of pregnant women from Auckland, New Zealand. Women who had lower socioeconomic status and who experienced ethnic discrimination had higher evening cortisol in late pregnancy and gave birth to infants with elevated cortisol reactivity and altered gene regulation (methylation) profiles. These findings are consistent with the hypothesis that maternal social environment impacts maternal and offspring biology. Notably, the types of stress exposures that impacted cortisol in the present study are relatively novel from an evolutionary perspective. Thus the evolved capacity for an intergenerational transfer of information could be maladaptive in the contemporary ecology when activated in response to structural inequalities within society. Future research evaluating diverse sources of stress and a range of biological responses in offspring are necessary to clarify whether modifications in offspring biology reflect adaptation or biological impairment.

Grant Year: 
2011
Award Amount: 
$24,935

Abrams, Elizabeth T.

Grant Type: 
Dissertation Fieldwork Grant
Insitutional Affiliation: 
Michigan, Ann Arbor, U. of
Status: 
Completed Grant
Approve Date: 
September 13, 2001
Project Title: 
Abrams, Elizabeth T., U. of Michigan, Ann Arbor, MI - To aid research on 'Variability in Birth Outcome following Malaria during Pregnancy,' supervised by Dr. A. Roberto Frisancho

ELIZABETH T. ABRAMS, while a student at the University of Michigan in Ann Arbor, Michigan, was awarded a grant in September 2001 to aid research on variability in birth outcomes following malaria during pregnancy, under the supervision of Dr. A. Roberto Frisancho. Malaria infections during pregnancy are associated with a number of poor birth outcomes, including intrauterine growth retardation, preterm delivery, and fetal death. Previous researchers had identified malaria-induced immune responses and birth outcomes, but the immune response to malaria could not fully account for the variation in birth outcomes. Abrams focused on a second potential determinant of poor birth outcomes: maternal and fetal iron status. She examined umbilical-cord hemoglobin levels in 33 malaria-infected and 57 uninfected women delivering in Blantyre, Malawi, in relation to maternal hemoglobin levels, malaria status, neonatal inflammation, and birth outcome. Although, as expected, maternal hemoglobin levels were significantly decreased by malaria infection during pregnancy, there was no reduction in cord levels, nor was there any significant relationship between the two. Nevertheless, cord ferritin levels were elevated in the neonates of malaria-infected mothers in relation to increased parasitemia, suggesting fetal immune activation to maternal malaria. Increased cord ferritin was associated with significantly decreased birth weight and gestational length, although maternal and cord hemoglobin levels and malaria status had no effect on birth outcome. The markers of fetal hypoxia that were examined, including erythropoietin, cortisol, and corticotrophin-releasing hormone, were not altered in malaria-infected versus uninfected women. In sum, in this population, cord hemoglobin levels were buffered from the effects of maternal malaria. However, elevated cord ferritin levels suggested fetal immune activation to malaria, which appeared to influence birth outcomes.

Publication Credits:

Abrams, Elizabeth T., and Julienne N. Rutherford. 2011. Framing Postpartum Hemorrhage as a Consequence of Human Placental Biology: An Evolutionary and Comparative Perspective. American Anthropologist 113(3):417-430.

Abrams, Elizabeth T. and Elizabeth M. Miller. 2011. The Roles of the Immune System in Women's Reproduction: Evolutionary Constraints and Life History Trade-Offs. Yearbook of Physical Anthropology 54:134-154.

Abrams, Elizabeth T., et al 2005. Malaria during Pregnancy and Fetal Haematological Status in Blantyre, Malawi. Malaria Journal 4(39):1-8.

Grant Year: 
2001
Award Amount: 
$10,500

Eisenberg, Daniel Thomas Abraham

Grant Type: 
Dissertation Fieldwork Grant
Insitutional Affiliation: 
Northwestern U.
Status: 
Completed Grant
Approve Date: 
May 3, 2010
Project Title: 
Eisenberg, Daniel Thomas Abraham, Northwestern U., Evanston, IL - To aid research on 'Ecological Predictors of Telomere Lengths: A Longitudinal and Cross-population Analysis of Human Biological Diversity,' supervised by Dr. Christopher W. Kuzawa

DAN EISENBERG, then a student at Northwestern University, Evanston, Illinois, received a grant in May 2010 to research on 'Ecological Predictors of Telomere Lengths: a Longitudinal and Cross-Population Analysis of Human Biological Diversity,' supervised by Dr. Christopher Kuzawa . Telomeres are DNA sequences at chromosome ends that shorten with age and are required for proper cell division. Telomere shortening is associated with diminished cell proliferation capacity, which is believed to be a cause of senescence. Given the importance of cell proliferation to blood telomere length (BTL), it has been hypothesized that BTL reflects previous immune system activation and indicates current immune function. Thus BTL could provide a new biomarker of life history allocations and of developmental exposures to infection. Contrary to the shortening of BTL that occurs with age, previous studies have shown that children of older fathers have longer telomeres. By analyzing BTL data from the Philippines, Eisenberg and colleagues showed for the first time that this happens across at least two generations: older fathers not only have offspring with longer telomeres, but their sons also have offspring with longer telomeres. Analyses of how early life infection and growth predicts later BTL are ongoing.

Publication credit:

Eisenberg, Dan. 2012. Delayed Paternal Age of Reproduction in Humans is Associated with Longer Telomeres across Two Generations of Descendants. PNAS Early Edition (published online).

Grant Year: 
2010
Award Amount: 
$8,240

Indriati, Etty

Grant Type: 
Int'l Collaborative Research Grant
Insitutional Affiliation: 
Gadjah Mada U.
Status: 
Completed Grant
Approve Date: 
May 30, 2008
Project Title: 
Indriati, Dr. Etty, Gadjah Mada U., Indonesia; and Leonard, Dr. William, Northwestern U., IL - To aid collaborative research on 'Energetic Nutritional and Dental Health of Foragers Orang Rimba in the Sumatran Forest, Indonesia'

DR. ETTY INDRIATI, Gadjah Mada University, Jakarta, Indonesia, and DR. WILLIAM LEONARD, Northwestern University, Evanston, Illinois, were awarded an International Collaborative Research Grant to aid collaborative research on 'Energetic Nutritional and Dental Health of Foragers Orang Rimba in the Sumatran Forest, Indonesia.' This research examined dietary consumption, energy expenditure, body size, and other health measures in 85 men and 115 women agriculturists from Ngilo-Ilo, East Java. The adults of this population are short and light (159.9 cm, 51.8kg for men; 147.7cm, 45.8kg for women), with little evidence of a secular trend when compared to data collected on other rural Javanese populations in the 1960-70s. In contrast, urban Javanese today are significantly taller and heavier than their rural counterparts( 164.24 cm, 62 kg in males; 155.02cm, 52 kg in females; Indriati, 2002).BMIs are low in the Ngilo-Ilo population (20.3 kglm2 for men; 20.5 kglm2 for women).Despite high levels of growth stunting and low BMIs, body fatness in this population falls within normal ranges. These findings suggest that the standard WHO BMI cut-offs for obesity are not appropriate for small-bodied populations of Indonesia. Despite evidence of chronic energy stress, measured RMRs did not significantly differ from those predicted using WHO norms, suggesting no increased metabolic efficiency. In contrast, it appears that chronic health problems are on the rise in this population as28%ofthe sample had elevated cholesterol, and one third was hypertensive.

Grant Year: 
2008
Award Amount: 
$35,000

Noback, Marlijn Lisanne

Grant Type: 
Dissertation Fieldwork Grant
Insitutional Affiliation: 
Eberhardt-Karls U.
Status: 
Completed Grant
Approve Date: 
April 18, 2011
Project Title: 
Noback, Marlijn Lisanne, Eberhard Karls U., Tubingen, Germany - To aid research on 'Climate- and Diet-related Variation in Human Functional Cranial Components,' supervised by Dr. Katerina Harvati

MARLIJN NOBACK, then a student at Eberhard Karls University, Tubingen, Germany, was awarded a grant in April 2011 to aid research on 'Climate- and Diet-Related Variation in Human Functional Cranial Components,' supervised by Dr. Katerina Harvati. This study seeks to elucidate the physiological basis of craniofacial variation and the selective forces driving modern human cranial geographic diversity. Funding enabled the CT scanning of 45 individual crania from three different collections based in Paris, London, and Tübingen. These scans form part of a larger database of over 330 CT scans, representing populations from different climatic and dietary regimes. With the use of the software package AVIZO and a high performance laptop, 3D models of functional facial components are developed from the CT scans. Analyses are currently undertaken and include studies of variation and co-variation of the cranial components and their relation to diet and climate. This project will enhance understanding of the biological processes underlying the evolution of modern human anatomy, adaptation and geographic diversity.

Grant Year: 
2011
Award Amount: 
$18,060